Protein Details: Neuronal acetylcholine receptor subunit alpha-10

Protein ID

ICDB_Pro_1519

Protein Name

Neuronal acetylcholine receptor subunit alpha-10

Gene Name

CHRNA10

Organism

Gallus gallus (Chicken)

Length

452 amino acids

AlphaFoldDB

AF-Q9I8C7-F1-model_v4.pdb

Function

Ionotropic receptor with a probable role in the modulation of auditory stimuli. .

Sequence

MGSAPLPACLLALSLAGTVLAPGCGAAQGRLAHKLLHDLFANYSSALRPAEDTERALNVTLQVTLSQIIDMDERNQVLTSYLWVRQAWLDAHLAWDKDAYGGIDSIRIPSSYVWRPDIVLYNNADERFGGSMETNVVLRSDGHIMWDSPAITKSSCKVDVSYFPFDGQQCRLTFGSWTYNGNQIDLRNLLDTGDLTDFVENVEWEVLGMPATRNVVTYGCCSEPYPDVTYTLLLRRRASFYIFNLLLPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMPPSESVPLIGKYYIATMTMITASTALTIFIMNIHHCGPGARPVPPWARRLILHHLARALCVCEVGESCGRPQREGTGGMGPRDPPGEGVEPGLCPRSRCLCHHHAVLSSVGYIAGVFRRHRTAQRRAAEWKKVAKVMDRFFMWVFFLMVFLMSVLVIGKAA

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

SITE 33: "Involved in the interaction with the conotoxin GeXXA"

Disease

Location

DOI ID

RefSeq

NP_001094506.1